Loading ...
FGC – for you –> SARS-CoV-2 structural proteins trigger periodontal fibrosis
In a recent study posted to the bioRxiv* preprint server, researchers examined the pathological impacts of the structural components of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on human periodontal cells and tissue to understand the association between coronavirus disease 2019 (COVID-19) and deteriorating oral health.
Overall, the study provided novel insights into the impact of SARS-CoV-2 infections on periodontal health. The results revealed that the SARS-CoV-2 membrane and envelope proteins alter fatty acid degradation pathways in the mitochondria that are essential to maintain energy homeostasis. The dysregulation of the mitochondrial ?-oxidation pathway leads to the hyperproliferation of periodontal fibroblasts, causing fibrosis, and increased apoptosis and senescence. These results could contribute to a better understanding of the long COVID symptoms manifesting in other organ systems and provide targets for treatment.
AM SURE YOU ARE THRILLED! NOT PEER REVIEWED BTW………
Bullshit
Still no internet here
But had to respond
Not seeing any unusual increase in perio
Bullshit