COVID-19 is a treatable disease
Early treatment is ESSENTIAL to a good outcome (this is critical)
3. COVID-19 is a treatable disease; it is inappropriate to limit therapy to “supportive care” alone. Furthermore, it is likely that there will not be a single “magic bullet” to treat COVID-19. Rather, we should be using multiple drugs/interventions that have synergistic and overlapping biological effects that are safe, cheap and “readily” available. The impact of COVID-19 on middle- and lowincome countries will be enormous; these countries will not be able to afford expensive designer molecules. 4. The pulmonary phase
11. For prophylaxis and treatment of the early symptomatic phase, we suggest the combination of Quercetin (a plant polyphenol), Vitamin C and Zinc. This is based on intriguing basic-science data, which indicates that: a. Zinc is essential for innate and adaptive immunity.[9] In addition, Zinc inhibits RNA dependent RNA polymerase in vitro against SARS-CoV-2 virus.[8] b. Quercetin has direct viricidal properties against a range of viruses, including SARS-CoV2.[2,6] In addition, quercetin acts as a zinc ionophore. [137] c. Vitamin C improves the potency of Quercetin and its antiviral activity.[2]
12. It should also be noted that Vitamin D may be a very powerful prophylactic and treatment strategy against COVID-19. [17-24] Vitamin D deficiency explains, in part, the enormous geographic variation in mortality of this disease.
“COVID-19 is a treatable disease; it is inappropriate to limit therapy to “supportive care” alone.” as FDA, CDC, and WHO recommends.
This study does not have the characteristics one ideally likes. One ideally likes the combined results of multiple prospective double blinded studies, randomized performed at multiple centers. This is a collection of retrospective observational studies and opinions about them from one group (from my all-too-quick skim.
None of it is in my specialized professionalized background.
However it rings true (or potentially true, worthy of consideration) in multiple respects. As far as I can tell, it is biologically plausible (and I do know my way about biology to a fair degree, rather more than penny gold stocks). It emphasizes timing and patient selection. There is no touting of absolute cures, but rather modulations of well-known, well-described physiological and pathophysiological processes after a fashion that would be in keeping with generally known biology, at least to my somewhat naive (but not at all entirely naive) background.
I have a couple of observations to make based on the politics of science and medicine.
First, it is likely just since it’s hard to get everything perfect that some details here and there are not quite right at a minimum. Maybe much is incorrect. However, since if this protocol proves in the main to be correct, important people will have egg on their face (and perhaps certain drug companies won’t be able to sell what they want to sell), there may be attempts to fixate on possible problems with the protocol, even tiny problems, to try to discredit it all. If not, perhaps the 1st cousin of someone who wrote it wore an inappropriate necktie 30 years ago.
Second, it is quite possible that this protocol will not have an easy time getting studied in a rigorous fashion, at least in the US or anywhere via grant money disbursed by international bodies controlled by the US. It is noteworthy that the authors are not at one of the US’s most famous medical centers by any means. Even if they had had time to write grant proposals, they would have had hard times getting them accepted and funded. Or so think I cynically.
Third, although I tend strongly to be against much of the US military (especially anything other than pure, pure defense) I have noted –I hate to write it in many ways, but it is true– that the US military often are less rigid than other parts of the US medical establishment when it comes to medical and scientific research. If the protocol is tested in the US I would guess it might be with US military funding. (I have not checked to see whether this group has something like DARPA ties–maybe they have.)
I do not know whether this or that other country and its medical establishment is worse or better in being rigid and conformist. I do not know the others.
But in short I have no idea how much of it might be correct.
IT IS CORRECT. This is what frontline doctors are using to save lives. No this is not a scientific study. This is the real thing. This was put together by 8 of the USAs top medical universities. Is CDC and FDA listening? Apparently not.
Karl….this is not a study
This is a protocol that 8 medical universities have been using on the frontline. They new as early as April 6th when they published their first protocol that CDC WAS WRONG to not recommend early treatment. THIS IS NOT A STUDY. READ (BETTER YET – PRINT) THE PDF FILE.
I erred it calling it a study. It is a protocol. I had read it before, a pretty long time ago. I had not studied carefully enough to realize that it was the result of 8 medical universities’ work. I apologize for any errors.
There may be residual value in my comments after error is removed. Again, it seems to be the combined results of retrospective study that is biologically plausible and worthy of rather more positive attention that it has received and, I am afraid, may receive. The wheels of medicine, at least in the US, grind much too slowly.
“This is a protocol that 8 medical universities have been using on the frontline. ”
—————————————————————————————–
which 8? I can’t find any reference that states that.
“EVMS CRITICAL CARE COVID-19 MANAGEMENT PROTOCOL Developed and updated by Paul Marik, MD”
“The EVMS (East VA Medical School) Medical Group is providing guidance for healthcare providers treating COVID-19 patients. This approach to COVID-19 is based on the best (and most recent) available literature and the Shanghai Management Guideline for COVID.”
Kemmrich….. The Front Line COVID-19 Critical Care Consortium consisted of 8 Medical Universities as early as April 6th. And now there are 10. https://covid19criticalcare.com/team/
Fabulous Find PK
Thank you
This is groundbreaking news.
Don’t just sit back and wait to see what happens …like the CDC and FDA and WHO recommend
DO SOMETHING DAMMIT !
Try stuff and see how it works
That’s what these Doctors are doing.
Don’t sit around and wait for ambiguous peer reviewed double blind studies that may be publisjed and then often retracted while people are suffering and dieing.
Don’t sit around and wait for new drugs whichwill cost $1000 a pill
Don’t sit and wait for a vaccine…NO coronavirus vaccine has been created in 20 years of trying.
1…PREVENTION ( STRATEGIES TO IMPROVE YOUR IMMUNITY
2…EARLY TREATMENT..STRATEGIES TO MITIGATE THE SEVERETY
3…FULL ON TREATMENT TO PREVENT DEATH
These doctors have done the research …on live patients…not in vitro or on rats
They have had successes and failures and are learning on the fly and are confident enough to publish a protocol of cheap drugs and supplements which have worked.
There is NO one treatment but there are many to try.
The response to this from the WHO et all will be telling
will they
1…Endorse these protocols with credit and thanks to this “Consortium”
2… remain silent and tacitly NOT endorse it.
3… Attack it ?
Notice the Doctors are not politicicizing this
They do not endorse the use of Hydrochloroquine BUT they do endorse the use of Dexamethasone …which Does actually have a doube blind study proving it’s effectiveness and the WHO et all have NOT commented on it.
The WHO et all have EGG on their Collective FACES…as they are out of the loop here.
They have not commissioned any of these treatment protocols. In Other Words They are useless pieces of shit !
We need to be getting our information from the likes of this Group of Diverse and Respected University Doctors with NO affiliation with Big PHARMA nor Gates NOR WHO nor any political party.
Just REAL Doctors who are doing what they were trained and licenced to do
TREAT DISEASE with any means possible .
ANYBODY HERE HAVE A PROBLEM WITH THIS APPROACH?
Would anyone here refuse an attempt by one of these doctors to save their or a loved one’s life with a combination of these protocols VS a LUNG MACHINE that has proven to kill ! ?
….
…..
That’s what I thought
Thanks again PK .
A Fantastic beacon of hope and common sense finally !
Bravo to the Critical Care Consortium ( CCC)
PREVENTION IS THE NUMBER ONE THING HERE…VIT D3 VITC QUERCITIN ZINC VIT B1 AND YOUR IMMUNE SYSTEM !
Screw the WHO !
Thanks for your endorsement Fully. I can tell that you have read the pdf. Those who have not read it….., do so at their own peril.
The link you refer to is simply the list of doctors and the medical universities that make up this consortium. I suggest that you print out the actual protocol (13 pages) and you will find that this pdf is very complete and it will answer all of the questions you state above. Download and print here https://www.evms.edu/media/evms_public/departments/internal_medicine/EVMS_Critical_Care_COVID-19_Protocol.pdf
Has anyone here visited the FDA website? Viewed recommendations for patients? Viewed recommendations for doctors and frontline workers? FDA recommends to send patients home until they are sick enough to be hospitalized. Then the patient only gets “supportive care” until they need a ventilator. The website specifically says that there is no approved therapy because scientific studies have not been completed. The media will not tell you about what I have posted here. “Early treatment is ESSENTIAL to a good outcome (this is critical) COVID-19 is a treatable disease; it is inappropriate to limit therapy to “supportive care” alone.”
Nah…that’s called research…who needs research when you can just sit and watch the Chief Medical Wizards all day every day on the Death Channel tell you to wash your hands and wear your masks and wait for them to tell you what you can and cant do and with whom you can do it with…Be True to YOUR Social Circle
Remember to shut the lid before you Flush
Remember to wear a mask when having sex !
Perfect summary: For prophylaxis and treatment of the early symptomatic phase, we suggest the combination of Quercetin (a plant polyphenol), Vitamin C and Zinc. This is based on intriguing basic-science data, which indicates that: a. Zinc is essential for innate and adaptive immunity.[9] In addition, Zinc inhibits RNA dependent RNA polymerase in vitro against SARS-CoV-2 virus.[8] b. Quercetin has direct viricidal properties against a range of viruses, including SARS-CoV2.[2,6] In addition, quercetin acts as a zinc ionophore. [137] c. Vitamin C improves the potency of Quercetin and its antiviral activity.[2]
My family are taking all these supplements daily.
FDA,CDC and WHO recommendations … they can stick it where the sun does not shine.