“Many seek to attack my bona fides as a way of countering my logic and messaging. This is not about me. It is about lives. Your lives. This is not a game. This UK government expert report was recently updated. I recommend that you read it carefully.”

https://twitter.com/RWMaloneMD/status/1421845774330212358

“Can we predict the limits of SARS-CoV-2 variants and their phenotypic consequences?
As eradication of SARS-CoV-2 will be unlikely, we have high confidence in stating that there
will always be variants. The number of variants will depend on control measures.

We describe hypothetical scenarios by which SARS-CoV-2 could further evolve and acquire,
through mutation, phenotypes of concern, which we assess according to possibility. For this
purpose, we consider mutations in the ‘body’ of the virus (the viral genes that are expressed
in infected cells and control replication and cell response), that might affect virus fitness and
disease severity, separately from mutations in the spike glycoprotein that might affect virus
transmission and antibody escape.

We assess which scenarios are the most likely and what impact they might have and consider
how these scenarios might be mitigated. We provide supporting information based on the
evolution of SARS-CoV-2, human and animal coronaviruses as well as drawing parallels with
other viruses.”