Loading ...Chloroquine : The Smoking Gun
Thanks to Chris in Ontario for Digging this Up. From a 2005 study published in the Journal “Virology” for The National Center for Biotechnology Information U.S.
Snip
“Chloroquine is a potent inhibitor of SARS coronavirus infection and spread
Martin J Vincent,1 Eric Bergeron,2 Suzanne Benjannet,2 Bobbie R Erickson,1 Pierre E Rollin,1 Thomas G Ksiazek,1 Nabil G Seidah,2 and Stuart T Nichol
This article has been cited by other articles in PMC.
Background
Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.
Results
We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.
Conclusion
Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
Thats all we need to know but here is the whole study :
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1232869/
An Now The Snake denies this drug which costs next to nothing and is safer than aspirin has any use whatsoever ? Why ?
Is there still anyone here who doesn’t want to question the Party Line ? Why ?
To neglect this study and its conclusions and not to have used this medication as a prophylactic for Health Care Workers and an early treatment for so many who went on to die horrible deaths …is Murder !
Health Care Workers Should be made aware of this and they will be PISSED !
Pass it On
I really wasn’t going to comment (negatively) on any of these threads, because it doesn’t really matter — but I did look at HCQ usage on SARS and MERS.
Here is the definitive statement in your post: “Chloroquine is effective in preventing the spread of SARS CoV in (primate) cell culture.” In research, this is only the first step in a long line of steps that prove/disprove whether a treatment is effective and safe. What primates, what cells, what side effects, …? The bottom line is that “cell culture” doesn’t really mean much. Bleach works on a cell culture.
Here’s an article you may (or may not be interested in:
https://www.msn.com/en-us/health/medical/why-hydroxychloroquine-and-chloroquine-don-t-block-sars-cov-2-infection-of-human-lung-cells/ar-BB176RNt
All the”3rd world” countries are using HCQ and all of the first world countries are not.
Many of the 3rd world countries can get it like aspirin…over the counter
Look up the death rates per million …where are the highest and where are the lowest >?
Look at Africa where this drug is used by so many to combat endemic malaria…very low case rates .
Anecdotally did you notice we have a poster here who is a medical doctor who got covid…but his wife did not…and coincidentally she is on HCQ for a medical condition.
There are many doctors all over the world who are reporting great success with HCQ Zithromax and Zinc.
Some with thousands of cases reported.
There are peer reviewed studies which show it works and the 2 leading studies that show it doesnt had to be “retracted” for fraud.
Thats a LOT of evidence.
it is all on the sidebar for you to explore.
Your credibility is poor here since you stated there were hundreds of RCT studies to show masks are effective…I have challenged you to provide only 100 of them …so far NONE.
Until you can provide these your credibility is zero in my book.
That study you cited was commissioned by whom ? MSN …Microsoft Network …hmmm
And BTW…How is it you never / rarely comment on TA topics…You just lie in wait of something anti establishment to pounce on. Sounds like a Troll to me.
Those that can research will become researchers , sometimes for many long hours
Those that cannot will spend no time at all and become cheap critics.
The former are creative and the later are destructive.
I will not pretend to know about the effectiveness of the chloroquine group of meds in COVID-19.
I do know that they are widely used in many countries against it. One reason was that it was used for SARS1, so China and other eastern Asian countries found it easy to on its use once again as did other countries’ medical establishments who had looked at SARS1.
Anecdotally, with COVID-19 it was said that the Chinese found it interesting — but not surprising — that their lupus patients — who of course were on hydroxychloroquine — were doing pretty well in the COVID-19 epidemic in Wuhan early on. (I wasn’t there so I don’t know whether this anecdote is true!)
I also know that the response to hydroxychloroquine in the US has been off. Its proponents have been incorrect at times in presenting it as if harmless. People with certain hereditary blood problems can have significant problems with it. After long term use people can have some retinal changes — I know someone who had to stop it after a number years of daily use because of supposed minimal retinal changes affecting color vision that that person did not notice.
However the real anti-human SLIME and lying propaganda came from the big-lie media, the usual culprits who wanted to emphasize how dangerous it allegedly was to score cheap political points for utterly vicious purposes. No. It is routinely given as a safe drug for multitudes of people, day after day, year after year for many years, as something to “spare” people with rheumatologic disease from having to take steroids, which are a pretty routine set of drugs albeit with complications.
Hydroxychloroquine and related meds are well known with a well-known safety profile from years of use at different dosages from use in treating malaria and other parasitic diseases before they were used for rheumatologic disease.
100% with you on the conclusion. For the honest person denying HCQ when there is no known alternatives can be construed as murder. If you MSM oriented this denial is called good politics.
Big thanks again and again for providing this information.
If this was a legal case this article would be a bombshell. It confirms the clinical results of doctors like Dr. Immanuel who claim that not only does it fight the infection it also prevents it –all back in 2005, 15 years ago!
The Frontline doctors also said 200mg twice a week was enough for prophylaxis, a concentration the article also says was adequate, which is a common dosage for malaria prophylaxis.
“The inhibitory effects observed on SARS-CoV infectivity and cell spread occurred in the presence of 1–10 ?M chloroquine, which are plasma concen-trations achievable during the prophylaxis and treatment of malaria (varying from 1.6–12.5 ?M) [26] and hence arewell tolerated by patients….Our data provide evidence for the possibility of using the well-established drug chloroquine in the clinical management of SARS.”
It sets the stage for clinical trials, which I assume were never done, until now.
Anyone steering people away from HCQ now is as Hearst said, a murderer. This I’m sure is why the MSM moved so fast and hard against the Frontline Doctors video and website. We’re dealing with people who are willing to kill.
Ohio Board of Pharmacy Reverses Rule, Okays Hydroxychloroquine After Governor’s Request
https://www.breitbart.com/politics/2020/07/30/ohio-board-of-pharmacy-reverses-rule-okays-hydroxychloroquine-after-governors-request/
I guess a doctor in Ohio could prescribe it but the pharmacy wouldn’t give it to you! Pharmacists overruling prescriptions… Just what Frontline doctors were saying.
Wow..great find…thats encouraging
Pharmacists overuling Doctors …how pathetic is that.
These assholes are even trying to destroy that very important relationship
I recently prescribed it for my daughter because I wanted to have some on hand.
I wasn’t sure how the pharmacy would react since my profession doesn’t use it routinely.
So I called it in to the pharmacy i have been using for 45 years
No Problem
🙂
Socialism is great, if you know people….who know people….who know people………………..
One more point to make here.
The reason there were not human trials to follow up this research in 2005 was because by the time this was known Sars1 ….(which was a very big concern here in Toronto area as we had a high % of the world cases for some reason)…
miraculously and mysteriously
Disappeared.
Isn’t that amazing but isn’t that strange ?
It was killing 10% of those diagnosed !
But after less than a 1000 world wide deaths…it just freaking DISAPPEARED !
AND NO ONE KNOWS WHY
it gets better folks: fauci was head of NIH then… hmmm
The Virology Journal – the official publication of Dr. Fauci’s National Institutes of Health – published what is now a blockbuster article on August 22, 2005, under the heading – get ready for this – “Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.” (Emphasis mine throughout.) Write the researchers, “We report…that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage.”
This means, of course, that Dr. Fauci (pictured at right) has known for 15 years that chloroquine and it’s even milder derivative hydroxychloroquine (HCQ) will not only treat a current case of coronavirus (“therapeutic”) but prevent future cases (“prophylactic”). So HCQ functions as both a cure and a vaccine. In other words, it’s a wonder drug for coronavirus. Said Dr. Fauci’s NIH in 2005, “concentrations of 10 ?M completely abolished SARS-CoV infection.” Fauci’s researchers add, “chloroquine can effectively reduce the establishment of infection and spread of SARS-CoV.”
wait thats not totally correct he is NOW head of NIH so it was known…..