“In the long term, people who take the vaccine will be far more vulnerable to any mutations in the spike protein that might come along, even if they have already been infected and recovered once, or more than once.”

Page 23 – “Seropositivity estimates for S antibody in blood donors are likely to be higher than would be
expected in the general population and this probably reflects the fact that donors are more likely
to be vaccinated. Seropositivity estimates for N antibody will underestimate the proportion of the
population previously infected due to (i) blood donors are potentially less likely to be exposed to
natural infection than age matched individuals in the general population (ii) waning of the N
antibody response over time and (iii) recent observations from UK Health Security Agency
(UKHSA) surveillance data that N antibody levels appear to be lower in individuals who acquire
infection following 2 doses of vaccination.”

https://assets.publishing.service.gov.uk/government/uploads/system/uploads/attachment_data/file/1027511/Vaccine-surveillance-report-week-42.pdf